What side effects may I notice from receiving Imbruvica?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions (skin rash, itching or hives; swelling of the face, lips, or tongue)
-anemia
-bleeding (bloody or black, tarry stools; red or dark brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eyes, gums, or nose)
-heart failure (trouble breathing; fast, irregular heartbeat; sudden weight gain; swelling of the ankles, feet, hands; unusually weak or tired
-heartbeat rhythm changes (trouble breathing; chest pain; dizziness; fast, irregular heartbeat; feeling faint or lightheaded, falls)
-infection (fever, chills, cough, sore throat, pain or trouble passing urine)
-kidney injury (trouble passing urine or change in the amount of urine)
-thrombocytopenia
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-bone pain
-diarrhea
-mouth sores
-muscle cramps, pain
-nausea
-tiredness

This list may not describe all possible side effects for Imbruvica. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.