Imipramine

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: May 31, 2023

Common Questions


Common Questions about Imipramine


Is imipramine used for sleep?

Imipramine is not approved to treat insomnia (difficulty falling asleep and staying asleep). However, this medicine can cause drowsiness as a side effect. Also, it can improve sleep by treating depressive symptoms.



Is imipramine good for anxiety?

Imipramine is not usually prescribed to treat anxiety. There are other medications that can more effectively treat anxiety, such as duloxetine (Cymbalta) and fluoxetine (Prozac). However, imipramine is sometimes used off-label to treat panic disorder, a type of anxiety disorder.



How quickly does imipramine relieve depression?

Like most antidepressants, it takes imipramine 4-6 weeks to relieve depression. If you do not notice any improvement in severe depression after this length of time, tell your doctor. They may increase your dose or switch you to another antidepressant.



Why can’t I suddenly stop imipramine?

Suddenly stopping imipramine can cause withdrawal symptoms such as headache, nausea, and feeling unwell. Your doctor will tell you how to lower the dose gradually. 



Is there a difference between imipramine hydrochloride and imipramine pamoate?

Both imipramine hydrochloride and imipramine pamoate contain the same active ingredient. However, imipramine hydrochloride is approved to treat depression in adults and adolescents as well as bedwetting in children. On the other hand, imipramine pamoate is only approved to treat depression in adults.



What is the price of imipramine without insurance?

Without insurance, imipramine can be as high as $36.99, but with a free BuzzRx prescription discount coupon, you could pay as low as $10.66 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.



What is the price of imipramine with insurance?

Ask your pharmacist or insurance provider for your copay price on imipramine—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for imipramine. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.