Integra Plus

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Nov 14, 2024

Integra Plus Drug Details


Generic Name:

Multivitamin with iron

Common Brands:

Integra Plus, Ferralet 90, Taron Forte

Availability:

Prescription only

Therapeutic Class:

Dietary supplements

Forms:

Capsule

Administration:

By mouth

Therapeutic Uses:

Iron deficiency anemia

Controlled Status:

Not a controlled substance


Integra Plus Drug Class

Integra Plus (in-tee-grah plus) is a dietary supplement (multivitamin with iron)

Integra Plus Age Range

Integra Plus is approved for use in adults and children 12 years of age and older. The safety and efficacy of this medication have not been established in pediatric patients under 12 years of age.

Integra Plus Uses


Integra Plus Uses

Integra Plus tablets are used to treat iron deficiency anemia (low red blood cell count), for example, due to menorrhagia (heavy menstrual bleeding) or excessive blood loss, and during puberty, pregnancy, advanced age, or extended convalescence. It may also be used to treat folate deficiency and conditions in which iron deficiency and vitamin C deficiency occur together. 

There may be other uses of Integra Plus—your doctor or pharmacist can give you further information.

Integra Plus Mechanism of Action

Integra Plus contains two different forms of iron compounds—ferrous fumarate and polysaccharide iron complex. Studies have shown that this combination of orally ingested iron provides a higher level of iron replacement with fewer side effects. Integra Plus also contains B vitamins, folic acid, and vitamin C.

Integra Plus Doses

Integra Plus is available as a capsule to take by mouth. Each capsule contains ferrous fumarate and polysaccharide iron complex, which provide 125 mg of elemental iron, as well as B vitamins, vitamin C, and folic acid. The recommended dose for people above 12 years of age is 1 capsule daily, taken between meals. 

No clinical studies have been done in older adults (age 65 and over) who took Integra Plus, so we don’t know if older persons respond differently to this supplement compared to younger persons. In general, the dosage of all medications should be at the lower end of the usual dosage scale for elderly persons and people with concomitant diseases such as decreased hepatic function (liver disease), renal impairment (kidney disease), or decreased cardiac function (heart disease).

Integra Plus Directions


How To Use Integra Plus

Integra Plus comes in the form of a capsule that can be taken by mouth. You should take it between meals. However, if it causes an upset stomach, you can take it after meals. The medicine is best absorbed if you take it at bedtime. 

Read the prescription label carefully and take Integra Plus exactly as directed. Do not exceed the recommended dosage (take larger or more frequent doses) without talking to your healthcare provider.

Read the labels of all your over-the-counter dietary supplements. Many supplements contain iron and multiple vitamins. Taking multiple iron-containing products can lead to too much iron in the body, which can be harmful.

Missed dose: If you miss a dose of Integra Plus, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the next dose according to your regular dosing schedule. Do not take a double dose or extra medicine to make up for a missed dose.

Storage: Store Integra Plus at room temperature between 15-30° C or 59-86° F, away from moisture, heat, and direct light in a tightly closed container. Do not store medications in bathroom cabinets where they can be exposed to moisture and heat. Keep Integra Plus and all medications safely out of reach of children. Accidental iron poisoning is the leading cause of fatal poisoning in children under 6. In case of an accidental overdose, call a doctor or poison control center immediately.

Unused medicine: Dispose of unused Integra Plus in a way that children, other people, and pets cannot get to them. Do not throw Integra Plus in the trash or toilet. The safest way to properly discard expired or unneeded Integra Plus is through a drug take-back program or your local waste disposal company. Learn more about proper medication disposal

NOTEThis medication guide is a summary and may not contain all possible drug information on Integra Plus. The information contained here may not be up-to-date. This sheet is for information purposes only. If you have questions about Integra Plus, talk to your doctor or pharmacist for medical advice.


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Integra Plus Side Effects


Integra Plus Side Effects

Possible side effects of Integra Plus are listed below. Call your doctor if these side effects are severe or do not go away in a few days.

  • Stomach discomfort
  • Loss of appetite
  • Nausea
  • Diarrhea
  • Constipation

More severe reactions can also occur occasionally. Call your doctor immediately or seek emergency medical attention if you develop:

  • An allergic reaction with skin rash, itching, hives
  • Swelling of the lips, tongue, or throat
  • Trouble breathing or swallowing

The above list may not include all the potential side effects of Integra Plus. Tell your doctor if the side effects are unusual or severe or last more than a few days. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.

Integra Plus Overdose: The estimated overdose level of iron is 300 mg/kilogram of body weight. In case of an overdose of Integra Plus, call your doctor immediately. You can also call the National Poison Control Center at 1-800-222-1222. Call 911 if a person has difficulty breathing, cannot be awakened, has collapsed, or has had a seizure. 

Signs and symptoms of acute overdosage of Integra Plus may include nausea, vomiting, pale skin, bluish tinge to the hands and feet, black, tarry stools, drowsiness, coma, cardiovascular collapse, and even death in severe cases. 

For treatment of an overdose, doctors may use chelating agents and an exchange transfusion as specific therapy. They may also perform gastric lavage with sodium bicarbonate solution or milk to flush medications out of the stomach. In addition, they may administer intravenous fluids and electrolytes and give supplemental oxygen for the general management of other symptoms.

Source: FDA


Integra Plus Warnings


Integra Plus Risks, Warnings, and Complications


Taking Integra Plus can lead to serious adverse effects in some people. Some of the risks of taking this prescription multivitamin and iron supplement include:

  • CONTRAINDICATIONS: People with a known hypersensitivity to any of the active or inactive ingredients in Integra Plus should not take this prescription dietary supplement. It is also contraindicated in people with iron overload disorders such as hemosiderosis and hemochromatosis. In addition, people with hemolytic anemias and pernicious anemia should not take Integra Plus. This supplement contains folic acid, which can obscure pernicious anemia (mask the signs and symptoms). Folic acid alone is not the proper treatment for pernicious anemia and other megaloblastic anemias—these conditions need to be treated with both folic acid and vitamin B12 supplementation together. Taking folic acid alone can lead to hematological remission while the neurological manifestations remain progressive.

  • ACCIDENTAL OVERDOSE: An accidental overdose of iron-containing products is a leading cause of deadly poisoning in children under 6. Keep iron supplement tablets and all medications safely out of reach of children. Seek immediate medical help if you suspect a child has overdosed on iron tablets.


Precautions Before Starting Integra Plus

Tell your healthcare provider if you have ever had an allergic reaction to Integra Plus, any of the active or inactive ingredients in Integra Plus capsules, other iron supplements, or any other drugs. Your pharmacy can give you a list of ingredients.

Give your doctor and pharmacist a complete list of your medications, including prescription drugs, over-the-counter medicines, vitamins, supplements, and herbal products. This can help avoid possible drug interactions.

Give your doctor a complete medical history. Integra Plus may not be safe for people with certain medical conditions, such as iron overload disorders (hemochromatosis or hemosiderosis) and hemolytic anemias. It may be the improper therapy for megaloblastic anemias.

Tell your doctor if you are pregnant, could be pregnant, are planning a pregnancy, or are breast-feeding.

Precautions During Use of Integra Plus

Keep all your healthcare appointments while taking Integra Plus. Your doctor may order certain lab tests to check your iron levels and monitor your response to treatment.

Tell your doctor if you become pregnant while taking Integra Plus.

Integra Plus Drug Interactions

Interactions between Integra Plus and other medications can affect how they work and/or increase the risk of severe adverse reactions.

Give your doctor or pharmacist a complete list of your medications, including prescription drugs, OTC (non-prescription) medications, dietary supplements, and herbal remedies. Also, tell your healthcare professionals if you smoke, drink alcohol, or use recreational drugs because some of these substances can cause serious health complications when used with dietary supplements and prescription medications.

Integra Plus Pros & Cons


Integra Plus Pros and Cons

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  • Integra Plus contains iron and multiple vitamins in one capsule.
  • You only need to take it once daily.
  • It contains two forms of iron—ferrous fumarate and polysaccharide iron complex. Studies show this combination is better absorbed with fewer side effects.
  • Integra Plus contains vitamin C, which improves iron absorption.

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  • Iron supplements can cause gastrointestinal disturbances, including stomach discomfort, nausea, diarrhea, and constipation.
  • Oral administration of iron supplementation works more slowly than parenteral administration (injectable forms) in correcting a deficiency.

Integra Plus Pharmacist Tips


Integra Plus Tips from Pharmacists

  • You should take Integra Plus between meals, ideally at bedtime, because iron is better absorbed on an empty stomach. But if Integra Plus causes stomach upset, it may help to take it after meals.

  • Iron supplements can make stool appear darker, but this is harmless. But call your doctor immediately if you notice blood in the stool.

  • Read the labels of all your dietary supplements. Many different brands of multivitamins contain iron, along with other nutrients. Taking multiple iron-containing products can result in an overdose.

  • Integra Plus is not for pediatric use. Call the poison control center immediately if a child ingests this medicine accidentally. Accidental iron poisoning can result in fatal poisoning in children under 6 years of age.

Integra Plus Rx Savings Tips


Integra Plus Rx Savings Tips

Integra Plus is a brand-name medication. Brand-name drugs and generic drugs contain the same medicine and are equally effective and safe. Like with most medications, the generic version offers better value. However, there is no generic version available for Integra Plus. A BuzzRx Integra Plus coupon can result in big savings on the brand name of this prescription dietary supplement. With a BuzzRx discount card, savings card, or discount coupons, Integra Plus could cost you a fraction of retail prices. Integra Plus may be under $26.50 for 30 capsules of the 125 mg iron - 1 mg dose at Walmart, Walgreens, Rite Aid, CVS Pharmacy, and other participating pharmacies with a BuzzRx discount card or free coupon. For the biggest discounts on Integra Plus, give the checkout clerk your BuzzRx Integra Plus discount coupon when you drop off your prescriptions at the pharmacy counter.


Lowest Price for Integra Plus
Brand
$26.08
Generic
N/A

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Pricing based on most commonly-filled versions. Select the strength and quantity of your medication for the most accurate pricing.

Integra Plus Common Questions


Common Questions about Integra Plus


What is the best time to take Integra Plus?

The best time to take Integra Plus is between meals, ideally at bedtime.



Who should not take Integra Plus?

People who have had an allergic reaction to Integra Plus or any of the active or inactive ingredients in this formulation in the past should not take it. Also, iron supplements are not for people with an iron overload disorder or hemolytic anemia.



Does Integra Plus cause constipation?

Constipation can be a side effect of taking Integra Plus. Drink plenty of water and eat a high-fiber diet. Talk to your doctor about taking a stool softener or laxative to relieve occasional constipation.



How to raise iron levels quickly?

Parenteral administration (intravenous infusion of iron) raises iron levels faster than oral administration (taking iron supplementation by mouth).



What is the price of Integra Plus without insurance?

Without insurance, Integra Plus can be as high as $41.32, but with a free BuzzRx prescription discount coupon, you could pay as low as $26.08 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.



What is the price of Integra Plus with insurance?

Ask your pharmacist or insurance provider for your copay price on Integra Plus—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for Integra Plus. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.