Isotretinoin

Last Reviewed: Sep 17, 2024

Pharmacist Tips


Isotretinoin (Absorica) Tips from Pharmacists

  • When you first start treatment with isotretinoin, your acne may get worse before it gets better. Continue taking the medicine even if you don’t notice any immediate improvement.

  • Wear sunscreen and protective clothing while on this medicine.

  • Avoid driving at night while on isotretinoin.

  • Keep your medical and laboratory appointments. Your provider will want to order laboratory testing for liver function, blood glucose, and lipids. They will also order monthly pregnancy tests if you are a woman who can become pregnant.

  • Do not donate blood while on isotretinoin and for one month afterwards.

  • Call your healthcare provider immediately if you notice any sudden or unusual changes in mood or behavior while on this medicine.

  • Make sure you understand all the conditions of the iPLEDGE pregnancy registry. Talk to your doctor about an appropriate birth control method while on this medicine. Stop isotretinoin and call your doctor immediately if pregnancy occurs or is suspected. Also, tell your healthcare provider if you experience irregularities in your menstrual period such as breakthrough bleeding.