What side effects may I notice from receiving Janumet XR?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-feeling faint or lightheaded, falls
-joint pain
-redness, blistering, peeling or loosening of the skin, including inside the mouth
-signs and symptoms of heart failure like breathing problems, fast, irregular heartbeat, sudden weight gain; swelling of the ankles, feet, hands; unusually weak or tired
-signs and symptoms of low blood sugar such as feeling anxious, confusion, dizziness, increased hunger, unusually weak or tired, sweating, shakiness, cold, irritable, headache, blurred vision, fast heartbeat, loss of consciousness
-signs and symptoms of muscle injury like dark urine; trouble passing urine or change in the amount of urine; unusually weak or tired; muscle pain; back pain
-slow or irregular heartbeat
-unusual stomach upset or pain
-vomiting
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-diarrhea
-gas
-headache
-heartburn
-metallic taste in mouth
-nausea
-runny or stuffy nose
-sore throat
-upset stomach

This list may not describe all possible side effects for Janumet XR. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.