Do not take this medicine with any of the following medications:

-ceritinib
-certain antibiotics like chloramphenicol, clarithromycin, dalfopristin; quinupristin, telithromycin
-certain antiviral medicines for HIV or AIDS like atazanavir, cobicistat, darunavir, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, tipranavir
-certain medicines for fungal infection like ketoconazole, itraconazole, posaconazole, voriconazole
-conivaptan
-idelalisib
-mifepristone
-nefazodone
-ribociclib
-tucatinib
This medicine may also interact with the following medications:

-desmopressin
-digoxin
-fluconazole
-grapefruit juice
-rifampin

They need to know if you have any of these conditions:

-cannot feel if you are thirsty
-dehydration
-kidney disease
-liver disease
-low or high levels of sodium in the blood
-prostate disease
-an unusual or allergic reaction to tolvaptan, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your health care provider for regular checks on your progress. Tell your health care provider if your symptoms do not start to get better or if they get worse.
Check with your health care provider if you have severe diarrhea, nausea, and vomiting, or if you sweat a lot. The loss of too much body fluid may make it dangerous for you to take this drug.
You may need blood work done while you are taking this drug.

Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused drug after the expiration date.