Do not take this medicine with any of the following medications:

-live virus vaccines

This medicine may also interact with the following medications:

-biologic medicines such as abatacept, adalimumab, anakinra, certolizumab, etanercept, golimumab, infliximab, ofatumumab, rituximab, secukinumab, tocilizumab, tofacitinib, and ustekinumab
-birth control pills
-certain medicines for cholesterol like atorvastatin, lovastatin, and simvastatin
-certain medicines that treat or prevent blood clots like warfarin, apixaban, and rivaroxaban
-medicines that lower your chance of fighting infection
-steroid medicines like prednisone or cortisone
-theophylline

They need to know if you have any of these conditions:

-cancer
-diabetes
-diverticulitis
-hepatitis B or history of hepatitis B infection
-high cholesterol
-immune system problems
-infection (especially a virus infection such as chickenpox, cold sores, or herpes)
-liver disease
-low blood counts, like low white cell, platelets, or red cell counts
-recently received or scheduled to receive a vaccine
-scheduled to have surgery
-stomach or intestinal problems
-tuberculosis, a positive skin test for tuberculosis or have recently been in close contact with someone who has tuberculosis
-an unusual or allergic reaction to sarilumab, other medicines, foods, dyes or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse. You may need blood work done while you are taking this medicine.

This medicine may increase your risk of getting an infection. Call your health care professional for advice if you get a fever, chills, or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This medicine decreases your body''s ability to fight infections. Try to avoid being around people who are sick. Call your health care professional if you are around anyone with measles, chickenpox, or if you develop sores or blisters that do not heal properly.

Talk to your health care professional if you have not had chickenpox or the vaccine for chickenpox.

If you are going to need surgery or other procedure, tell your health care professional that you are using this medicine.

Talk to your doctor about your risk of cancer. You may be at risk for certain types of cancers if you take this medicine.

Keep out of the reach of children.

Store in the prefilled syringes or pens in the refrigerator at 2 to 8 degrees C (36 to 46 degrees F). Do not freeze. Do not shake. Keep in the original container to protect from light. Throw away any unopened and unused medicine that has been stored in the refrigerator after the expiration date.

If needed, the syringe or pen may be stored at room temperature up to 25 degrees C (77 degrees F) for up to 14 days. Keep in the original carton. Do not shake. Throw away any unused medicine that is stored at room temperature after 14 days.