Do not take this medicine with any of the following medications:

-biologic medicines such as adalimumab, certolizumab, etanercept, golimumab, infliximab
-live virus vaccines

This medicine may also interact with the following medications:

-abatacept
-baricitinib
-medicines that lower your chance of fighting an infection
-rilonacept
-rituximab
-sarilumab
-tocilizumab
-tofactinib

They need to know if you have any of these conditions:

-cancer
-immune system problems
-infection (especially a virus infection such as chickenpox, cold sores, or herpes)
-kidney disease
-low blood counts, like white cells
-lung or breathing disease, like asthma
-recently received or scheduled to receive a vaccine
-tuberculosis, a positive skin test for tuberculosis or have recently been in close contact with someone who has tuberculosis
-an unusual or allergic reaction to anakinra, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Your condition will be monitored carefully while you are receiving this medicine. Tell your doctor or health care professional if your symptoms do not start to get better or if they get worse. You may need blood work done while you are taking this medicine.

You will be tested for tuberculosis (TB) before you start this medicine. If your doctor prescribed any medicine for TB, you should start taking the TB medicine before starting this medicine. Make sure to finish the full course of TB medicine.

This medicine may increase your risk of getting an infection. Call your doctor or health care professional for advice if you get a fever, chills, or sore throat, or other symptoms of a cold or flu. Do not treat yourself. Try to avoid being around people who are sick.

Keep out of reach of children.

Store the syringes in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Do not freeze. Do not shake. Keep in the original container to protect from light. Do not use the medicine after the expiration date.