Korlym
Warnings
What may interact with Korlym?
Do not take this medicine with any of the following medications:
-certain medicines for fungal infections like fluconazole, ketoconazole, posaconazole
-certain medicines for high cholesterol like lovastatin, simvastatin
-cisapride
-cyclosporine
-dronedarone
-ergot alkaloids like dihydroergotamine, ergotamine
-fentanyl
-pimozide
-quinidine
-sirolimus
-tacrolimus
-thioridazine
This medicine may also interact with the following medications:
-certain antibiotics like clarithromycin, erythromycin, telithromycin
-certain antivirals for HIV or hepatitis
-certain medicines for seizures like carbamazepine, phenytoin, phenobarbital
-certain medicines that treat or prevent blood clots like warfarin
-conivaptan
-grapefruit juice
-hormonal birth control pills, injections, patches and devices
-itraconazole
-medicines for depression or anxiety
-narcotic medicines for pain
-other medicines that prolong the QT interval (cause an abnormal heart rhythm)
-repaglinide
-rifabutin
-rifampin
-rifapentine
-St. John''s wort
-steroid medicines like prednisone or cortisone
-thyroid hormones
-voriconazole
What should I tell my health care provider before I take Korlym?
They need to know if you have any of these conditions:
-bleeding disorder
-cancer
-depression
-diabetes that is not related to Cushing''s disease
-heart disease
-high blood pressure
-liver disease
-low levels of potassium in the blood
-organ transplant
-taking steroids such as dexamethasone or prednisone
-unexplained vaginal bleeding
-an unusual or allergic reaction to mifepristone, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding
What should I watch for while using Korlym?
Visit your doctor or health care professional for regular checks on your progress. You will need blood work done while you are taking this medicine.
This medicine may affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.
Keep the MedGuide for this medicine. If you need emergency medical care, show your healthcare provider the MedGuide. Tell the health care provider that you have taken this medicine.
Female patients will need a pregnancy test prior to starting this medicine. Do not become pregnant while taking this medicine or for 1 month after stopping it. Patients should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information.
Female patients must use effective birth control with this medicine. Use a non-hormonal form of birth control while taking this medicine and for 1 month after stopping it. Talk to your health care professional about how to prevent pregnancy. Tell your doctor right away if you think you may be pregnant.
Do not breastfeed an infant while taking this medicine.
Where should I keep my medicine?
Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medicine after the expiration date.
To get rid of medicines that are no longer needed or have expired:
-Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put it in the trash, empty the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
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