Warnings


What may interact with LENVIMA?

Do not take this medicine with any of the following medications:

-cisapride
-dronedarone
-pimozide
-thioridazine
This medicine may also interact with the following medications:

-alfuzosin
-bedaquiline
-certain antibiotics like azithromycin, clarithromycin or erythromycin
-certain medicines for bladder problems like solifenacin, tolterodine
-certain medicines for depression, anxiety, or psychotic disturbances
-certain medicines for fungal infections like ketoconazole, posaconazole, voriconazole, fluconazole, and itraconazole
-certain medicines for irregular heart beat like amiodarone, dofetilide, flecainide, propafenone, quinidine
-chloroquine
-ciprofloxacin
-dofetilide
-ezogabine
-fingolimod
-granisetron
-leuprolide
-lopinavir; ritonavir
-methadone
-metronidazole
-mifepristone
-octreotide
-ondansetron
-other medicines that prolong the QT interval (cause an abnormal heart rhythm) like ziprasidone
-pasireotide
-pentamidine
-promethazine
-quinine
-ranolazine
-rifampin
-rilpivirine
-romidepsin
-saquinavir
-tacrolimus
-telavancin
-telithromycin
-tetrabenazine
-tizanidine
-toremifene
-vardenafil
-vorinostat

What should I tell my health care provider before I take LENVIMA?

They need to know if you have any of these conditions:

-dental or gum disease
-diabetes (high blood sugar)
-high blood pressure
-heart disease
-blood clots
-irregular heartbeat or rhythm
-low levels of calcium, magnesium, or potassium in the blood
-inflammatory bowel disease
-kidney disease
-liver disease
-protein in your urine
-having or recent surgery
-thyroid disease
-an unusual or allergic reaction to lenvatinib, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using LENVIMA?

Visit your doctor for regular check-ups. Report any side effects. Continue your course of treatment unless your doctor tells you to stop. You will need blood work done while you are taking this medicine.
Do not become pregnant while taking this medicine or for 30 days after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 1 week after stopping it. This medicine may interfere with the ability to have a child. Talk with your doctor or health care professional if you are concerned about your fertility.
Before having surgery, talk to your health care provider to make sure it is ok. This drug can increase the risk of poor healing of your surgical site or wound. You will need to stop this drug for 1 week before surgery. After surgery, wait at least 2 weeks before restarting this drug. Make sure the surgical site or wound is healed enough before restarting this drug. Talk to your health care provider if questions.
Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.
This medicine may interfere with the ability to have a child. You should talk with your doctor or health care professional if you are concerned about your fertility.

Where should I keep my medicine?

Keep out of the reach of children.
Store between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.