Levonorgestrel-Eth Estradiol
Medically Reviewed by Dr. Harshi Dhingra, M.D.
Last Reviewed: Nov 01, 2023
Side Effects
Levonorgestrel and Ethinyl Estradiol Side Effects
Common side effects of levonorgestrel and ethinyl estradiol are listed below. Tell your doctor if these side effects are severe or persist after a few days.
- Stomach cramps
- Nausea
- Vomiting
- Fluid retention and bloating
- Breast tenderness
- Spotting or irregular menstrual cycles
- Weight changes
- Headache
- Dizziness
- Depression
- Acne
- Unwanted hair growth
- Intolerance to contact lenses
Sometimes, levonorgestrel and ethinyl estradiol can cause more serious side effects that require immediate medical attention. Call your doctor without delay or seek emergency medical care if you experience:
- Skin rash, hives, itching, or swelling of the face, eyes, lips, tongue, or throat (allergic reactions)
- Blood clots (pain, swelling, or warmth in a leg, chest pain, shortness of breath)
- Severe stomach pain, nausea, vomiting, fever (gallbladder problems)
- Right upper stomach pain, nausea, loss of appetite, dark urine, light-colored stools, yellowing skin or eyes, unusual weakness (liver injury)
- Elevated blood pressure
- New or worsening headaches
- Sudden numbness or weakness, dizziness, confusion, difficulty speaking, difficulty walking, loss of balance or coordination, severe headache, vision changes (signs of stroke)
- Vaginal discharge, itching, or odor (yeast infection)
- Worsening depression or changes in mood
- Change in menstrual flow or unscheduled bleeding
The above list may not include all the potential adverse effects of levonorgestrel and ethinyl estradiol. Contact your healthcare professional if your side effects are unusual or severe or they do not get better over time. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.
Levonorgestrel and ethinyl estradiol Overdose: In case of an overdose of levonorgestrel and ethinyl estradiol, call your doctor immediately. You can also call the local poison control center or national poison control center at 1-800-222-1222. If a person cannot be awakened, has trouble breathing, has collapsed, or has had a seizure, call 911.
Source: FDA
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