-certain medicines for bowel problems or bladder incontinence (these can cause constipation)

They need to know if you have any of these conditions:

-history of stool (fecal) impaction
-now have diarrhea or have diarrhea often
-other medical condition
-stomach or intestinal disease, including bowel obstruction or abdominal adhesions
-an unusual or allergic reaction to linaclotide, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor for regular check ups. Tell your doctor if your symptoms do not get better or if they get worse.

Diarrhea is a common side effect of this medicine. It often begins within 2 weeks of starting this medicine. Stop taking this medicine and call your doctor if you get severe diarrhea.

Stop taking this medicine and call your doctor or go to the nearest hospital emergency room right away if you develop unusual or severe stomach-area (abdominal) pain, especially if you also have bright red, bloody stools or black stools that look like tar.

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep this medicine in the original container. Keep tightly closed in a dry place. Do not remove the desiccant packet from the bottle, it helps to protect your medicine from moisture. Throw away any unused medicine after the expiration date.