What side effects may I notice from receiving Makena?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-depressed mood
-increase in blood pressure
-increased hunger or thirst
-increased urination
-signs and symptoms of a blood clot such as breathing problems; changes in vision; chest pain; severe, sudden headache; pain, swelling, warmth in the leg; trouble speaking; sudden numbness or weakness of the face, arm or leg
-unusually weak or tired
-unusual vaginal bleeding
-yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-diarrhea
-fluid retention and swelling
-nausea
-pain, redness, or irritation at site where injected

This list may not describe all possible side effects for Makena. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.