Medroxyprogesterone Acetate
Medically Reviewed by Dr. Harshi Dhingra, M.D.
Last Reviewed: Jul 14, 2022
Pros & Cons
What are the pros and cons of Medroxyprogesterone Acetate (Provera)?
- Medroxyprogesterone acetate is available in a low-cost generic form.
- You only need to take this medicine once a day.
- It is a good alternative to progesterone (Prometrium) for people with a peanut allergy.
- Medroxyprogesterone has a protective effect on the uterus after menopause.
- Taking medroxyprogesterone with estrogen can increase the risk of blood clots, heart attack, stroke, and hormone-related cancer.
- This medicine can cause premenstrual-type symptoms, including headache, bloating, sleep difficulties, and mood changes.
- You need to take medroxyprogesterone on certain days of the month, which can be difficult to keep track of.
- Medroxyprogesterone can cause breakthrough bleeding or spotting even in postmenopausal women.
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