Methenamine Hippurate

( Hiprex )

Last Reviewed: Oct 25, 2024

Common Questions


Common Questions about Methenamine Hippurate (Hiprex)


Is methenamine hippurate an antibiotic?

Yes, methenamine hippurate is an antibiotic. However, it is not used to treat active urinary tract infections. Rather, it is used for long-term suppressive treatment and prevention of recurrent urinary tract infections. Your doctor will prescribe some other antibiotic to treat an active UTI.



What is the difference between methenamine hippurate and methenamine mandelate?

Both methenamine hippurate and methenamine mandelate contain the same active ingredient. However, methenamine hippurate (hippuric acid salt) is taken twice a day, morning and evening. In contrast, methenamine mandelate (mandelic acid salt) is taken four times a day, after meals and at bedtime.



Does methenamine make you pee more?

Methenamine should not make you pee more. However, large doses (8 grams a day or more taken for 3-4 weeks or longer) can cause urinary frequency and bladder irritation. Follow your doctor’s dosing instructions carefully to prevent side effects.



Do you have to take vitamin C with methenamine?

Vitamin C may help to make urine acidic and help methenamine work better. However, check with your doctor before taking vitamin C during methenamine treatment.



How long should I take methenamine?

Methenamine is for long-term treatment and prevention of recurrent urinary tract infections. You may need to take this medicine for 6 months or longer.



What is the price of methenamine without insurance?

Without insurance, methenamine can be as high as $131.99, but with a free BuzzRx prescription discount coupon, you could pay as low as $36.62 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.



What is the price of methenamine with insurance?

Ask your pharmacist or insurance provider for your copay price on methenamine—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for methenamine. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.