Methenamine Hippurate (Hiprex) Tips from Pharmacists

• You need to keep your urine acidic for methenamine to work properly. Talk to your healthcare provider about dietary modifications. They will recommend avoiding certain foods like milk and dairy products and certain medications like antacids that can make your urine less acidic.

• Drink plenty of water and stay well hydrated while on methenamine. This will help flush out bacteria from your urinary tract.

• Do not stop methenamine hippurate without talking to your doctor, even if you feel well and your UTI symptoms are gone. Stopping treatment of bacterial infections too soon or inappropriate antibiotic use can lead to antibiotic resistance and make urinary tract infections harder to treat in the future.