This medicine may also interact with the following medications:

-antiinflammatory drugs, NSAIDs like ibuprofen
-barbiturates like phenobarbital
-corticosteroids like prednisone
-lithium
-medicines for chest pain or angina
-medicines for diabetes
-medicines for high blood pressure or heart failure
-medicines to control heart rhythm
-prescription pain medicines
-rifampin
-skeletal muscle relaxants like tubocurarine
-some medicines for lowering cholesterol like colestipol or cholestyramine

They need to know if you have any of these conditions:

-circulation problems, or blood vessel disease
-decreased urine
-diabetes
-heart disease, heart failure or a history of heart attack
-kidney disease
-liver disease
-lung or breathing disease, like asthma
-pheochromocytoma
-slow heart rate
-thyroid disease
-an unusual or allergic reaction to metoprolol, hydrochlorothiazide, sulfa drugs, or other drugs, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor or health care professional for regular checks on your progress. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her.
Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.
This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.
Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care professional for advice. Some ingredients may increase your blood pressure.
Talk to your health care professional about your risk of skin cancer. You may be more at risk for skin cancer if you take this medicine.
This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Keep the container tightly closed. Throw away any unused drug after the expiration date.