-alcohol
-certain medicines for blood pressure, heart disease, irregular heart beat
-medicines that cause drowsiness or tiredness
-MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

They need to know if you have any of these conditions:

-Buerger''s disease
-depression
-heart disease
-irritated skin or open sores
-Raynaud''s phenomenon
-scleroderma
-Sjogren''s syndrome
-an unusual or allergic reaction to brimonidine, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Do not get this medicine in your eyes. If you do, rinse out with plenty of cool tap water.

If anyone, especially a child, accidentally swallows this medicine, they may have serious side effects and need to be treated in a hospital. Get medical help right away if anyone swallows this medicine and has lack of energy, trouble breathing or stops breathing, a slow heart beat, confusion, sweating, restlessness, muscle spasms, or twitching.

Keep out of the reach of children.

Store between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.