Do not take this medicine with any of the following medications:

-certain medicines for fungal infections like itraconazole, fluconazole, posaconazole, and voriconazole
-cisapride
-dextromethorphan; quinidine
-dronedarone
-pimozide
-quinidine
-thioridazine

This medicine may also interact with the following medications:

-acetazolamide
-antihistamines for allergy, cough and cold
-atropine
-bethanechol
-carbamazepine
-certain medicines for bladder problems like oxybutynin, tolterodine
-certain medicines for Parkinson''s disease like benztropine, trihexyphenidyl
-certain medicines for stomach problems like dicyclomine, hyoscyamine
-certain medicines for travel sickness like scopolamine
-cimetidine
-dexamethasone
-dofetilide
-hydrochlorothiazide (HCTZ)
-ketamine
-ipratropium
-metformin
-methazolamide
-nicotine
-NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
-other medicines for Alzheimer''s disease
-other medicines that prolong the QT interval (cause an abnormal heart rhythm)
-phenobarbital
-phenytoin
-ranitidine
-rifampin, rifabutin or rifapentine
-sodium bicarbonate
-succinylcholine
-triamterene
-ziprasidone

They need to know if you have any of these conditions:
-difficulty passing urine
-head injury
-heart disease
-irregular heartbeat
-kidney disease
-liver disease
-lung or breathing disease, like asthma
-seizures
-stomach or intestinal disease, ulcers or stomach bleeding
-an unusual or allergic reaction to donepezil, memantine, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor or health care professional for regular checks on your progress. Check with your doctor or health care professional if there is no improvement in your symptoms or if they get worse.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

If you are going to need surgery or other procedure, tell your doctor that you are using this medicine.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.