Do not take this medicine with any of the following medications:
-certain migraine medicines like ergotamine and dihydroergotamine
-medicines used to treat erectile dysfunction like sildenafil, tadalafil, and vardenafil
-riociguat

This medicine may also interact with the following medications:
-medicines for high blood pressure
-other medicines used to treat angina

They need to know if you have any of these conditions:
-liver disease
-low blood pressure, or low blood volume
-previous heart attack or heart failure
-an unusual or allergic reaction to nitroglycerin, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Check your heart rate and blood pressure regularly while you are using this medicine. Ask your doctor or health care professional what your heart rate and blood pressure should be and when you should contact him or her. Tell your doctor or health care professional if you feel your medicine is no longer having any effect.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep dry in a tightly sealed container. Heat and moisture can reduce the effectiveness of this medicine. Throw away any unused medicine after the expiration date.