Nitrofurantoin Monohydrate Macrocrystals (Macrodantin) Side Effects

Possible adverse effects of nitrofurantoin monohydrate macrocrystals are listed below. Call your doctor for medical advice if the side effects are severe or continue after a few days.

• Heartburn
• Gas
• Nausea
• Vomiting
• Loss of appetite
• Headache
• Hair loss

Some of the adverse effects of nitrofurantoin monohydrate macrocrystals are more serious. Call your doctor right away or seek emergency medical help if you develop the following serious side effects or notice signs and symptoms such as:

• Skin rash, hives, itching (signs of an allergic reaction)
• Swelling of the face, eyes, lips, tongue, or throat
• Difficulty breathing or swallowing
• Chest pain
• Fever or chills
• Cough that doesn’t go away
• Unusual tiredness or muscle weakness
• Numbness, tingling, burning, or prickling sensations in the fingers or toes
• Right upper stomach pain, fatigue, nausea, loss of appetite, yellowing of the skin or eyes, dark-colored urine
• Pale skin
• Dizziness
• Confusion
• Severe watery or bloody diarrhea which may be accompanied by stomach cramps and fever (this can happen up to 2 months or more after finishing antibiotic treatment)
• Eye pain or changes in vision

The above list may not include all the potential side effects of nitrofurantoin monohydrate macrocrystals. Contact your healthcare provider if the side effects are unusual or severe or they do not get better over time. You can also report unusual side effects or suspected adverse reactions to the Food and Drug Administration at 1-800-FDA-1088.

Nitrofurantoin monohydrate macrocrystals (Macrodantin) Overdose: In case of an overdose of nitrofurantoin monohydrate macrocrystals, call your doctor immediately. You can also call your local poison control center, provincial poison control center, or the national poison control center on 1-800-222-1222. Call 911 if someone has collapsed, is not responding, has stopped breathing, or has had a seizure.

Source: FDA