Do not take this medicine with any of the following medications:

-MAOIs like Marplan, Nardil, and Parnate

This medicine may also interact with the following medications:

-alcohol
-antihistamines for allergy, cough, and cold
-certain medicines for anxiety or sleep
-certain medicines for depression like amitriptyline, fluoxetine, sertraline
-certain medicines for seizures like phenobarbital, primidone
-dobutamine
-dopamine
-epinephrine
-general anesthetics like halothane, isoflurane, methoxyflurane, propofol
-isoproterenol
-medicines that relax muscles for surgery
-narcotic medicines for pain
-norepinephrine
-phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine

They need to know if you have any of these conditions:

-if you drink alcohol
-kidney disease
-liver disease
-low blood pressure
-narcolepsy
-schizophrenia
-sleep apnea
-an unusual or allergic reaction to opicapone, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your health care professional for regular checks on your progress. Tell your health care professional if your symptoms do not start to get better or if they get worse. Do not stop taking except on your health care professional''s advice. You may develop a severe reaction. Your health care professional will tell you how much medicine to take.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

When taking this medicine, you may fall asleep without notice. You may be doing activities like driving a car, talking, or eating. You may not feel drowsy before it happens. Contact your health care provider right away if this happens to you.

There are have been reports of increased sexual urges or other strong urges such as gambling while taking this medicine. If you experience any of these while taking this medicine, you should report this to your health care professional as soon as possible.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy and drinking plenty of water may help. Contact your health care professional if the problem does not go away or is severe.

Keep out of the reach of children.

Store at room temperature below 30 degrees C (86 degrees F). Throw away any unused medicine after the expiration date.