Orphenadrine Citrate ER

Last Reviewed: Sep 16, 2024

Orphenadrine Citrate ER Pros and Cons

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Orphenadrine starts working quickly, typically within an hour, to relieve pain from acute musculoskeletal conditions.
You only need to take it twice a day by mouth.
There is a lower-cost generic available.

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Orphenadrine is for short-term treatment of musculoskeletal pain. The safety of this medicine with continuous long-term therapy has not been established.
It typically induces anticholinergic effects such as dry mouth and constipation. You can also experience transient episodes of dizziness and lightheadedness.
Orphenadrine may not be the best choice for older adults and those with abnormal liver function values, glaucoma, gut problems, urination problems, or nerve or muscle problems.