Orphenadrine Citrate ER

Last Reviewed: Sep 16, 2024

Side Effects


Orphenadrine Citrate ER Side Effects

Possible side effects of orphenadrine are listed below. Call your doctor for medical advice if an adverse effect is severe or continues after a few days.

  • Dry mouth due to a mild anti-cholinergic action
  • Dizziness
  • Drowsiness
  • Blurred vision
  • Headache
  • Upset stomach
  • Constipation
  • Vomiting
  • Trouble with urination
  • Some of the adverse reactions of orphenadrine are more serious. Call your doctor right away or seek emergency medical help if you develop the following serious symptoms:
  • Skin rash
  • Fast heart rate
  • Mental confusion
  • Fainting
  • Hallucinations

The above list may not include all the potential side effects of orphenadrine. Contact your healthcare provider if the side effects are unusual or severe or they do not get better over time. You can also report suspected adverse reactions to the Food and Drug Administration at 1-800-FDA-1088.

Orphenadrine citrate ER Overdose: The minimum lethal dose of orphenadrine is 2-3 grams. In case of an overdose of orphenadrine, call your doctor immediately. You can also call your local poison control center, provincial poison control center, or the national poison control center on 1-800-222-1222. Call 911 if someone has collapsed, stopped responding, stopped breathing, or had a seizure. Orphenadrine toxicity symptoms may include emergent anticholinergic effects such as fast heartbeat, urinary retention, blurry vision, unusual excitement, stupor, or convulsions. An overdose may require hospitalization for appropriate supportive treatment.

Source: FDA