Phenytoin

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Sep 01, 2023

Pros & Cons


Phenytoin Pros and Cons

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  • Phenytoin is available in various dosage forms, such as extended phenytoin sodium capsules, chewable tablets, and oral suspension.
  • It is available in a lower-cost generic form.
  • Once you achieve good seizure control, you may only need to take phenytoin once a day.
  • Phenytoin is approved for use in children.

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  • You need regular monitoring of phenytoin serum concentrations.
  • This medication can lead to changes in mood and behavior and increase the risk of suicidal thoughts or behavior.
  • Some people develop severe, potentially life-threatening skin reactions to phenytoin.
  • It may cause changes in appearance, such as coarsening of facial features, unwanted hair growth, enlargement of the lips, and enlargement of the gums.
  • Phenytoin has drug interactions with many medications.