Warnings


What may interact with Pimozide?

Do not take this medicine with any of the following medications:

-certain antibiotics like azithromycin, clarithromycin, dirithromycin, erythromycin, telithromycin
-certain antivirals for HIV or hepatitis
-certain medicines for depression like citalopram, escitalopram, fluoxetine, paroxetine, sertraline, fluvoxamine, nefazodone, tricyclic antidepressants
-certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
-certain medicines for irregular heart beat like amiodarone, dofetilide, dronedarone, encainide, flecainide, propafenone, quinidine, sotalol
-chlorpromazine
-droperidol
-metoclopramide
-other medicines that prolong the QT interval (cause an abnormal heart rhythm) like dacomitinib, degarelix, encorafenib, entrectinib, eribulin, goserelin, lapatinib
-thioridazine
-zileuton
-ziprasidone
This medicine may also interact with the following medications:

-alcohol
-antihistamines for allergy, cough, and cold
-atropine
-certain medicines for anxiety or sleep
-certain medicines for bladder problems like oxybutynin, tolterodine
-certain medicines for stomach problems like dicyclomine, hyoscyamine
-certain medicines for travel sickness like scopolamine
-epinephrine
-general anesthetics like halothane, isoflurane, methoxyflurane, propofol
-grapefruit juice
-ipratropium
-levodopa or other medicines for Parkinson''s disease
-medicines for blood pressure
-medicines for seizures
-medicines that relax muscles for surgery
-narcotic medicines for pain
-stimulant medicines for attention disorders, weight loss, or staying awake

What should I tell my health care provider before I take Pimozide?

They need to know if you have any of these conditions:

-blockage in your bowel
-dementia
-diabetes
-difficulty swallowing
-have trouble controlling your muscles
-heart disease
-history of irregular heartbeat
-if you often drink alcohol
-kidney disease
-liver disease
-low blood counts, like low white cell, platelet, or red cell counts
-low blood pressure
-low magnesium level in the blood
-low potassium level in the blood
-Parkinson''s disease
-prostate disease
-seizures
-trouble passing urine
-an unusual or allergic reaction to pimozide, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using Pimozide?

Visit your health care professional for regular checks on your progress. Tell your health care professional if symptoms do not start to get better or if they get worse. Do not stop taking except on your health care professional''s advice.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can increase dizziness and drowsiness. Avoid alcoholic drinks.
This medicine may increase blood sugar. Ask your health care provider if changes in diet or medicines are needed if you have diabetes.
This drug can cause problems with controlling your body temperature. It can lower the response of your body to cold temperatures. If possible, stay indoors during cold weather. If you must go outdoors, wear warm clothes. It can also lower the response of your body to heat. Do not overheat. Do not over-exercise. Stay out of the sun when possible. If you must be in the sun, wear cool clothing. Drink plenty of water. If you have trouble controlling your body temperature, call your health care provider right away.

Where should I keep my medicine?

Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.