Primidone

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Apr 03, 2025

Common Questions


Common Questions about Primidone (Mysoline)


Is primidone the same as phenobarbital?

Phenobarbital is a minor metabolite (breakdown byproduct) of primidone. Meaning some primidone is converted to phenobarbital in the body.



Does primidone help essential tremors?

Yes, primidone can help in managing essential tremors, especially hand tremors. Along with the beta blocker propranolol, primidone is a first-line therapy for essential tremor.



Is primidone an antipsychotic?

No, primidone is not an antipsychotic. It is an anticonvulsant and is used to treat certain types of seizures. However, primidone has been found to benefit people with psychiatric conditions such as refractory bipolar disorder and may be used off-label for this purpose.



How quickly does primidone start working?

It can take 4-8 weeks for primidone to work properly and have its full effects. Continue taking primidone as prescribed. Tell your doctor if this medicine fails to control seizures after several weeks. Your doctor may adjust your dose or change you to a different medicine.



Can I drink alcohol while on primidone?

It’s best to avoid alcohol while on primidone. Alcohol can make side effects such as unsteadiness, dizziness, and double vision worse.



What is the price of primidone without insurance?

Without insurance, primidone can be as high as $55.95, but with a free BuzzRx prescription discount coupon, you could pay as low as $19.53 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.



What is the price of primidone with insurance?

Ask your pharmacist or insurance provider for your copay price on primidone—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for primidone. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.