Primidone

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Apr 03, 2025

Pros & Cons


Primidone (Mysoline) Pros and Cons

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  • Primidone can be used alone or as adjunctive therapy with other drugs to achieve seizure control.
  • There is a lower-cost generic available.

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  • Primidone is an older seizure medication, and there are newer, more effective medicines available for epilepsy treatment.
  • You need to take it 2-3 times daily.
  • It is only available in pill form.
  • It takes several weeks for primidone to have its full effects.
  • You may need regular blood tests to check plasma concentrations of the drug and make dosage adjustments.