Do not take this medicine with any of the following medications:

-aspirin and aspirin-like drugs
-certain medicines for fungal infections like itraconazole or ketoconazole
-clarithromycin
-erythromycin
-ketorolac
-methotrexate
-topiramate
This medicine may also interact with the following medications:

-acetaminophen
-alcohol
-antibiotics including penicillins, sulfonamides
-antiviral medicines such as acyclovir, famciclovir, ganciclovir
-cyclosporine
-epinephrine
-lorazepam
-meclofenamate
-medicines for diabetes
-medicines for sleep during surgery
-methenamine
-NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
-pyrazinamide
-rifampin
-sodium bicarbonate

They need to know if you have any of these conditions:

-anemia
-blood disorders like leukemia or lymphoma
-having an acute gouty attack
-heart disease
-immune system problems
-intestinal disease
-kidney disease, stones
-liver disease
-low platelet counts
-stomach problems
-an unusual or allergic reaction to probenecid, colchicine, other medicines, lactose, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor or health care professional for regular checks on your progress. You may need periodic blood checks.
Aspirin and non-steroidal antiinflammatory drugs like ibuprofen can make this medicine less effective. Do not treat yourself for headaches or pain. Ask your doctor or health care professional for advice.
Alcohol can increase the chance of getting stomach problems and gout attacks. Do not drink alcohol.
You may need to be on a special diet while taking this medicine. Check with your doctor. Also, ask how many glasses of fluid you need to drink a day. You must not get dehydrated.
This medicine may cause a decrease in vitamin B12. You should make sure that you get enough vitamin B12 while you are taking this medicine. Discuss the foods you eat and the vitamins you take with your health care professional.
This medicine can interfere with some urine glucose tests. If you use such tests talk with your health care professional.

Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.