Probenecid
Warnings
What may interact with Probenecid?
Do not take this medicine with any of the following medications:
-aspirin and aspirin-like medicines
-ketorolac
-methotrexate
-topiramate
This medicine may also interact with the following medications:
-acetaminophen
-alcohol
-antibiotics including penicillins, sulfonamides
-antiviral medicines such as acyclovir, famciclovir, ganciclovir
-certain medicines for gout like pegloticase
-lorazepam
-meclofenamate
-medicines for diabetes
-medicines for sleep during surgery
-NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
-pyrazinamide
-rifampin
What should I tell my health care provider before I take Probenecid?
They need to know if you have any of these conditions:
-acute gouty attack
-blood disorders or disease
-kidney disease, or kidney stones
-recent radiation therapy
-stomach ulcers
-an unusual or allergic reaction to probenecid, sulfa drugs, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding
What should I watch for while using Probenecid?
It may take several months before you see the full effect of this medicine. It is only effective if you keep taking it regularly even if you have an attack of gout. Your prescriber or health care professional will prescribe other tablets to treat an acute attack.
Aspirin and non-steroidal antiinflammatory drugs like ibuprofen can make this medicine less effective. Do not treat yourself for headaches or pain. Ask your doctor or health care professional for advice.
Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
You may need to be on a special diet while taking this medicine. Check with your doctor. Also, ask how many glasses of fluid you need to drink a day. You must not get dehydrated.
This medicine can interfere with some urine glucose tests. If you use such tests talk with your health care professional.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
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