What side effects may I notice from receiving Prometrium?

Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breast tissue changes or discharge
-changes in vaginal bleeding during your period or between your periods
-depression
-muscle or bone pain
-numbness or pain in the arm or leg
-pain in the chest, groin or leg
-seizures or tremors
-severe headache
-stomach pain
-sudden shortness of breath
-unusually weak or tired
-vision or speech problems
-yellowing of skin or eyes

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-acne
-fluid retention and swelling
-increased in appetite
-mood changes, anxiety, depression, frustration, anger, or emotional outbursts
-nausea, vomiting
-sweating or hot flashes

This list may not describe all possible side effects for Prometrium. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.