Prozac

Medically Reviewed by Harshi Dhingra, M.D.

Last Reviewed: Jun 24, 2022

Side Effects


What are Prozac (fluoxetine) side effects?

The most common side effects of Prozac are listed below. Contact your doctor if these side effects are severe or persistent.

  • Insomnia (difficulty falling asleep or staying asleep)
  • Headache
  • Drowsiness
  • Anxiety
  • Nervousness
  • Decreased libido (sex drive)
  • Nausea
  • Diarrhea
  • Heartburn
  • Dry mouth
  • Yawning
  • Weakness
  • Uncontrollable shaking
  • Loss of appetite
  • Weight loss
  • Excessive sweating
  • Confusion, difficulty concentrating, memory problems

Prozac can also cause serious side effects. Call your doctor right away if you experience:

  • Rash, hives, blisters, itching
  • Fever, shivering, sweating, agitation, confusion
  • Dizziness or fainting
  • Swelling in the throat, tongue, lips, face, hands, or feet
  • Difficulty breathing or swallowing
  • Fast, irregular, or slow heartbeat
  • Joint pain, severe muscle stiffness
  • Hallucinations
  • Seizures
  • Loss of coordination
  • Nausea, vomiting, diarrhea
  • Abnormal bruising or bleeding

The above list may not include all the potential side effects of Prozac. Talk to your doctor if you have severe side effects or the side effects do not improve over time. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.

Prozac Overdose: In case of a known or suspected overdose, call your doctor immediately. If the person can’t be awakened, has had a seizure, or has trouble breathing, call 911. Symptoms of Prozac overdose may include confusion, unsteadiness, nervousness, uncontrolled shaking, dizziness, pounding heartbeat, hallucinations, fever, fainting, and unresponsiveness. 

NOTE: Prozac is a prescription drug intended to be used only by you. Never share your prescription medication with others or use someone else’s Prozac.

Source: FDA