Do not take this medicine with any of the following medications:
-linezolid
-MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
-methylene blue (injected into a vein)

This medicine may also interact with the following medications:
-alcohol
-antiviral medicines for HIV or AIDS
-certain medicines that treat or prevent blood clots like warfarin
-certain medicines for depression, anxiety, or psychotic disturbances
-certain medicines for fungal infections like ketoconazole and itraconazole
-certain medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan
-certain medicines for seizures like carbamazepine or phenytoin
-certain medicines for sleep
-cimetidine
-erythromycin
-fentanyl
-lithium
-medicines for blood pressure
-nefazodone
-rasagiline
-rifampin
-supplements like St. John''s wort, kava kava, valerian
-tramadol
-tryptophan

They need to know if you have any of these conditions:
-bipolar disorder
-glaucoma
-kidney disease
-liver disease
-phenylketonuria
-suicidal thoughts
-an unusual or allergic reaction to mirtazapine, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Tell your doctor if your symptoms do not get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress. Because it may take several weeks to see the full effects of this medicine, it is important to continue your treatment as prescribed by your doctor.

Patients and their families should watch out for new or worsening thoughts of suicide or depression. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine may cause dry eyes and blurred vision. If you wear contact lenses you may feel some discomfort. Lubricating drops may help. See your eye doctor if the problem does not go away or is severe.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) Protect from light and moisture. Throw away any unused medicine after the expiration date.