Do not take this medicine with any of the following medications:

-atomoxetine
-certain antiviral medicines for HIV or AIDS
-dronedarone
-green tea
-levodopa
-MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
-procarbazine
-ranolazine
-sirolimus
-voriconazole

This medicine may also interact with the following medications:

-acetaminophen
-antacids
-atovaquone
-barbiturates like phenobarbital
-beta-blockers like metoprolol and propranolol
-calcium channel blockers like diltiazem, nifedipine and verapamil
-certain antibiotics like ciprofloxacin
-certain medicines for depression, anxiety, or psychotic disturbances
-certain medicines for diabetes, like glipizide or glyburide
-certain medicines for fungal infections like fluconazole, ketoconazole and itraconazole
-certain medicines for irregular heart beat like disopyramide, mexiletine, quinidine
-certain medicines for seizures like carbamazepine, phenobarbital, phenytoin, valproic acid
-certain medicines for sleep
-certain medicines that treat or prevent blood clots like warfarin
-chloramphenicol
-clarithromycin
-clofibrate
-cyclosporine
-dapsone
-diazepam
-digoxin
-doxycycline
-enalapril
-female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
-haloperidol
-levothyroxine
-methadone
-narcotic medicines for pain
-quinine
-sulfamethoxazole; trimethoprim
-steroid medicines like prednisone or cortisone
-tacrolimus
-theophylline

They need to know if you have any of these conditions:

-diabetes
-gout
-HIV or AIDS
-if you often drink alcohol
-kidney disease
-liver disease
-poor nutrition
-tingling of the fingers or toes, or other nerve disorder
-wear contact lenses
-an unusual or allergic reaction to isoniazid, rifampin, rifabutin, other medicines, foods, dyes or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Tell your doctor or health care provider if your symptoms do not start to get better or if they get worse.

This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.

Do not treat diarrhea with over the counter products. Contact your doctor if you have diarrhea that lasts more than 2 days or if it is severe and watery.

This medicine can color your teeth, urine, sweat, tears, and mucous. The color may stain your teeth for good. The color in tears may also stain soft contact lenses for good. If you wear contact lenses, ask your doctor or health care provider when you can use your lenses again.

You may need blood work done while you are taking this medicine.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.

This medicine may cause a decrease in vitamin D and vitamin B6. You should make sure that you get enough vitamins while you are taking this medicine. Discuss the foods you eat and the vitamins you take with your health care provider.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.