Directions
How To Use Rybelsus
Rybelsus comes as an oral tablet to take by mouth. You should take it first thing in the morning on an empty stomach, at least 30 minutes before eating or drinking anything or taking other oral medicines. Take a Rybelsus (semaglutide) tablet with no more than 4 ounces (120 mL) of plain water. Taking medications or eating or drinking within 30 minutes can affect Rybelsus by reducing its absorption and making it less effective.
Eat something 30 minutes after taking your Rybelsus (semaglutide) dose. Waiting more than 30 minutes to eat or drink after taking Rybelsus can lead to increased absorption of Rybelsus. Too much Rybelsus in your body can put you at risk of low blood sugar.
Do not cut, chew, or crush Rybelsus (semaglutide) tablets. If you are on the 14-mg dose of Rybelsus, do not take two of the 7-mg tablets to make a 14-mg dose.
Read the prescription label carefully and take Rybelsus exactly as prescribed. Do not change the dose or dosing frequency without consulting your healthcare provider.
Your doctor will start you on a low dose of Rybelsus and increase the dose every 4 weeks until you are on a maintenance dose that controls your blood sugar levels.
You should know that Rybelsus works alongside a calorie-restricted diet and increased physical activity to help control type 2 diabetes. This medication is not a cure for diabetes. Continue taking Rybelsus even if you feel well and your blood sugar levels are well controlled. Do not stop taking this medication without talking to your doctor.
Missed dose: If you miss a dose of Rybelsus, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take a double dose or extra medicine to make up for a missed dose.
Storage: Store Rybelsus (semaglutide) at room temperature (between 15-30° C or 59-86° F) away from moisture, heat, and direct light in its original container, tightly closed. Do not store medications in the bathroom where they can be exposed to moisture and heat. Keep all medications safely out of reach of children and pets.
Unused medicine: Unused Rybelsus should be disposed of in a way that other people, children, and pets cannot get to them. Do not throw Rybelsus in the trash or flush it down the toilet. The best way to dispose of expired or unneeded Rybelsus is through a drug take-back program or your local waste disposal company. Learn more about proper medication disposal.
NOTE: This sheet is a summary and may not contain all possible Rybelsus drug information. It is for educational purposes only and does not constitute medical advice. If you have questions about Rybelsus, talk to your doctor or pharmacist to ensure you receive proper medical care.
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