Rybelsus

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jan 09, 2025

Pharmacist Tips


Rybelsus Tips from Pharmacists

  • Take Rybelsus (oral semaglutide) on an empty stomach first thing in the morning, at least 30 minutes before eating or drinking anything or taking other oral medicines. Eat something 30 minutes after your Rybelsus dose. Take the medicine with no more than 4 ounces of plain water.

  • You should know that Rybelsus (semaglutide) works in conjunction with a reduced-calorie diet and exercise program.

  • If you are prescribed 14 mg of Rybelsus daily, take the 14-mg tablet. Do not use two 7-mg tablets instead.

  • Stomach pain, nausea, vomiting, and diarrhea are common side effects of Rybelsus treatment. Tell your doctor if these side effects are severe or continue after your body has had a chance to adjust to the medicine.