Rybelsus

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jan 09, 2025

Side Effects


Rybelsus Side Effects

Common side effects of Rybelsus are listed below. Tell your doctor if they are severe or do not go away after a few days.

  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach pain
  • Constipation
  • Heartburn
  • Burping
  • Decreased appetite

Rarely, Rybelsus can cause more serious side effects. Call your doctor right away or seek emergency medical care if you develop:

  • Signs and symptoms of a serious allergic reaction (skin rash, itching, hives)
  • Swelling of the face, eyes, lips, tongue, or throat 
  • Difficulty breathing or swallowing
  • Persistent stomach pain, with or without vomiting (stomach pain is usually in the upper left or middle part of the stomach and may spread to the back)
  • Swelling of the lower legs, ankles, or feet
  • Decreased urination
  • Vision changes
  • Lightheadedness, dizziness, drowsiness, headache, weakness, blurred vision, slurred speech, sweating, confusion, shakiness, jitteriness, fast heartbeat, irritability, anxiety, mood changes, or excessive hunger

The above list may not include all the potential side effects of Rybelsus. Call your doctor if you experience any severe or unusual symptoms. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.

Rybelsus Overdose: In case of an overdose, call your doctor, your local poison control center, or the national poison control center at 1-800-222-1222 immediately. Call 911 if a person has trouble breathing, can’t be awakened, has collapsed, or had a seizure.

Source: FDA