Sertraline (Zoloft) Side Effects

Possible side effects of sertraline are listed below. Tell your doctor if these side effects are severe or continue after a few days.

• Gastrointestinal side effects such as nausea, vomiting, diarrhea, constipation, heartburn
• Loss of appetite 
• Weight gain or weight loss
• Dry mouth
• Tiredness
• Dizziness
• Headache
• Uncontrolled movements
• Excessive sweating
• Nervousness
• Trouble sleeping (insomnia)
• Sexual problems in men and women, including decreased libido (sex drive), erection problems, ejaculation problems, or inability to have an orgasm

Sertraline can also cause more serious side effects. Call your doctor immediately or seek emergency medical attention if you develop the following symptoms:

• Convulsions or seizures
• Unusual bleeding or bruising
• Fever, sweating, confusion, agitation, hallucinations, shivering, fast heartbeat, muscle stiffness, muscle trembling, poor coordination, stomach upset, nausea, vomiting, diarrhea
• Weakness, headache, lack of balance, confusion, memory problems
• Eye pain, eye swelling, eye redness, vision changes, nausea
• Allergic reaction (skin rash, hives, itching)
• Swelling
• Chest pain
• Difficulty breathing

The above list may not include all the potential adverse effects of sertraline. Contact your healthcare professional if your side effects are unusual or severe or do not improve over time. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.

Sertraline (Zoloft) Overdose: In case of an overdose of sertraline, call your doctor immediately. You can also call the local poison control center or national poison control center at 1-800-222-1222. Call 911 if a person cannot be awakened, has trouble breathing, has collapsed, or has had a seizure. Symptoms of a sertraline overdose may include dizziness, drowsiness, tiredness, rapid, pounding, or irregular heartbeat, fever, sweating, confusion, agitation, hallucinations, severe muscle stiffness or twitching, abnormal excitement, or loss of consciousness.

Source: FDA