Shingrix

Medically Reviewed by HaVy Ngo-Hamilton, Pharm.D.

Last Reviewed: Jun 27, 2024

Uses


Shingrix Uses

Shingrix belongs to a class of drugs called Vaccines, Inactivated, Viral.

Shingrix (zoster vaccine recombinant, adjuvanted) is a prescription medicine used in  preventing shingles (herpes zoster). Shingrix can also help protect against herpes-zoster-related complications.

Shingrix is recommended for the prevention of shingles in adults aged 50 years and older and in adults aged 18 years and older who are at increased risk of herpes zoster virus (shingles) due to immunodeficiency or immunosuppression resulting from a known disease or treatment.

Shingrix is not indicated for the prevention of primary varicella infection

(chickenpox). The vaccine is not intended to treat shingles or its complications (post-herpetic neuralgia) but can only prevent them.

Shingrix may be used alone or with other medications.

There may be other uses of Shingrix—your pharmacist or doctor can give you further drug information.

Shingrix Mechanism of Action

Shingrix is a vaccine (inactivated) that provides protection from varicella-zoster virus, the virus that causes shingles. Shingrix acts by exposing you to a small dose of an inactive virus, which causes the body's immune system to produce antibodies against the virus. As a result, it aids in the development of your body's natural defenses against shingles and its complications. An active infection that has already developed in the body cannot be treated by this vaccine.

Shingrix Doses

Shingrix has a reconstituted dose of 0.5ml in 1 vaccine.

The typical dosage is 0.5 mL injected intramuscularly in 2 doses (0.5 mL each) by a healthcare provider.

Following the first dose, the final dose is administered after 2 to 6 months, however, can also be administered 1 to 2 months later in those with weak immune systems and who achieve benefits from a shorter vaccination schedule.