Do not take this medicine with any of the following medications:

-live virus vaccines

This medicine may also interact with the following medications:

-cyclosporine
-inactivated vaccines
-midazolam
-warfarin

They need to know if you have any of these conditions:

-Crohn''s disease
-immune system problems
-infection
-recently received or are scheduled to receive a vaccine
-suicidal thoughts, plans, or attempts
-tuberculosis, a positive skin test for tuberculosis, or have recently been in close contact with someone who has tuberculosis
-an unusual or allergic reaction to brodalumab, other medicines, foods, dyes or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Patients and their families should watch out for new or worsening depression or thoughts of suicide. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, call your health care professional.

You will be tested for tuberculosis (TB) before you start this medicine. If your doctor prescribes any medicine for TB, you should start taking the TB medicine before starting this medicine. Make sure to finish the full course of TB medicine.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body''s ability to fight infections. Try to avoid being around people who are sick.

This medicine can decrease the response to a vaccine. If you need to get vaccinated, tell your health care professional if you have received this medicine within the last 6 months. Extra booster doses may be needed. Talk to your doctor to see if a different vaccination schedule is needed.

Keep out of the reach of children.


Store the prefilled syringe in a refrigerator between 2 to 8 degrees C (36 to 46 degrees F). Keep the syringe in the original carton until ready for use. Protect from light. Do not freeze. Do not shake. Prior to use, remove the syringe from the refrigerator and use within 30 minutes. Throw away any unused medicine after the expiration date on the label.