Silver Sulfadiazine Pros and Cons
- Silver sulfadiazine has broad antimicrobial activity (it is effective against a wide range of gram-negative and gram-positive bacteria).
- Bacterial resistance against this drug is generally low.
- It can treat and prevent infectious complications in severe burns.
- Silver sulfadiazine may be an alternative for people who cannot use a carbonic anhydrase inhibitor such as mafenide.
- There is a lower-cost generic available.
- Silver sulfadiazine can cause severe dermatologic and allergic reactions in some people.
- Those with a sulfa allergy should not use this medicine.
- This drug is not safe for premature babies and infants under 2 months of age.
- It may not be safe for people with kidney or liver problems.
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