How To Use Sotalol (Betapace Af)

Sotalol comes as a tablet and oral solution to take by mouth 1 to 3 times a day as prescribed. Try to take sotalol at around the same times every day. You can take this medicine with or without food, but you should do so consistently.

You will likely need to stay in the hospital when you are first starting sotalol for at least 3 days or until steady state plasma concentrations of the drug are reached (steady drug levels in blood). This will need to be done in a medical facility that has cardiac resuscitation and continuous heart monitoring facilities as well as healthcare personnel who are trained in managing serious cardiac arrhythmias. 

Your doctor will perform a baseline ECG to measure your QT interval as well as blood tests to measure serum potassium and magnesium levels before starting sotalol treatment. They will also measure serum creatinine to ensure normal renal function (kidney function) and calculate the estimated creatinine clearance to calculate a safe dosing interval. People with reduced creatinine clearance (40 to 60 mL/min) may require less frequent dosing. Your QTc (QT interval) will need to be monitored every 2 to 4 hours after dose increments. 

Read the prescription label carefully and take sotalol exactly as advised. Do not change the dose or dosage frequency of the antiarrhythmic drug without your doctor’s approval.

Your doctor will start you on a low dose of sotalol and increase the dose gradually. Follow your doctor’s dosing instructions and take the medicine as directed by your doctor.

Sotalol can help to control your heart rhythm abnormality but will not cure the underlying condition. Continue treatment with sotalol even if you feel well. Do not stop taking sotalol suddenly - this can put you at an increased risk of serious heart problems, including ischemic heart disease, i.e., chest pain (angina) and heart attack. Your doctor will tell you how to reduce the dose slowly over 1-2 weeks while avoiding strenuous physical activity.

Missed dose: If you miss a dose of sotalol, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose according to your regular dosing schedule. Do not take a double dose or extra medicine to make up for a missed dose.

Storage: Store sotalol at room temperature (between 15-30° C or 59-86° F) away from moisture, heat, and direct light in a tightly closed container. Do not store medications in the bathroom, where they can be exposed to moisture and heat. Keep all medications safely out of reach of children and pets.

Unused medicine: Unused or expired sotalol should be disposed of in a way that children, other people, and pets cannot get to them. Do not throw sotalol in the trash or flush it down the toilet. The best way to dispose of expired or unneeded sotalol is through your local waste disposal company or a drug take-back program. Learn more about proper medication disposal. 

NOTE: This medication guide is a summary and may not contain all possible drug information on sotalol. The information contained here may not be up-to-date. This sheet is for information purposes only. If you have questions about sotalol, talk to your healthcare professionals for medical advice.

Discounted prices for sotalol (Betapace Af)
 start at $12.74.

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