-amiodarone
-aprepitant
-atazanavir
-captopril
-carbamazepine
-certain medicines for fungal infections like ketoconazole and itraconazole
-clarithromycin
-cyclosporine
-diltiazem
-erythromycin
-methylnaltrexone
-naloxone
-naltrexone
-phenytoin
-quercetin
-quinidine
-rifampin
-ritonavir
-saquinavir
-St. John''s Wort
-verapamil

They need to know if you have any of these conditions:

-cancer or tumor in abdomen, intestine, or stomach
-diverticulitis
-history of bowel blockage
-history of stomach ulcer
-inflammatory bowel disease
-kidney disease
-liver disease
-Ogilvie''s syndrome
-stomach or intestine problems
-an unusual or allergic reaction to naldemedine, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor for regular check ups. Tell your doctor if your symptoms do not get better or if they get worse.

Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.