-vaccines
-valproic acid

They need to know if you have any of these conditions:

-kidney disease
-liver disease
-an unusual or allergic reaction to temozolomide, dacarbazine (DTIC), other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.

You may need blood work done while you are taking this medicine.

Call your doctor or health care provider for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Call if you get diarrhea. Do not treat yourself. This drug decreases your body''s ability to fight infections. Try to avoid being around people who are sick.

This medicine may increase your risk to bruise or bleed. Call your doctor or health care provider if you notice any unusual bleeding.

Do not open the capsules of this medicine. Breathing in or touching the powder in the capsule may be harmful. If the powder accidentally gets on your skin, wash the area thoroughly. If you have difficulty swallowing, contact your doctor or health care provider.

Talk to your doctor about your risk of cancer. You may be more at risk for certain types of cancers if you take this medicine.

Do not become pregnant while taking this medicine or for at least 6 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care provider or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for at least 1 week after stopping it.

Men should not father a child while taking this medicine or for at least 3 months after stopping it. Contact your doctor right away if your partner becomes pregnant. Do not donate sperm while taking this medicine and for at least 3 months after you stop taking it.

This medicine may make it more difficult to father a child. Talk to your health care provider if you are concerned about your fertility.

Keep out of the reach of children.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.