Do not take this medicine with any of the following medications:

-MAOIs like Marplan, Nardil, and Parnate

This medicine may also interact with the following medications:

-alcohol
-apomorphine
-certain medicines for sleep or anxiety
-desipramine
-dobutamine
-dopamine
-epinephrine
-isoproterenol
-linezolid
-methyldopa
-narcotic medicines for pain
-norepinephrine
-warfarin

They need to know if you have any of these conditions:

-kidney disease
-liver disease
-mental illness
-narcolepsy
-sleep apnea
-an unusual or allergic reaction to tolcapone, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your health care professional for regular checks on your progress. Tell your health care professional if your symptoms do not start to get better or if they get worse. Do not stop taking except on your health care professional''s advice. You may develop a severe reaction. Your health care professional will tell you how much medicine to take. You may need blood work done while you are taking this medicine.

You may get dizzy or have difficulty controlling your movements. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy and drinking plenty of water may help. Contact your health care professional if the problem does not go away or is severe.

When taking this medicine, you may fall asleep without notice. You may be doing activities like driving a car, talking, or eating. You may not feel drowsy before it happens. Contact your health care provider right away if this happens to you.

There have been reports of increased sexual urges or other strong urges such as gambling while taking this medicine. If you experience any of these while taking this medicine, you should report this to your health care provider as soon as possible.

You should check your skin often for changes to moles and new growths while taking this medicine. Call your doctor if you notice any of these changes.

Keep out of the reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.