Do not take this medicine with any of the following medications:

-live virus vaccines

This medicine may also interact with the following medications:

-amoxapine
-certain medicines for depression, anxiety, or psychotic disturbances like amitriptyline, clomipramine, desipramine, doxepin, imipramine, maprotiline, nortriptyline, protriptyline, trimipramine
-codeine
-inactivated vaccines
-methadone
-pimozide
-thioridazine

They need to know if you have any of these conditions:

-immune system problems
-infection (especially a virus infection such as chickenpox, cold sores, or herpes) or history of infections
-recently received or scheduled to receive a vaccine
-tuberculosis, a positive skin test for tuberculosis, or have recently been in close contact with someone who has tuberculosis
-an unusual or allergic reaction to guselkumab, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Your condition will be monitored carefully while you are receiving this medicine. Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

You will be tested for tuberculosis (TB) before you start this medicine. If your doctor prescribes any medicine for TB, you should start taking the TB medicine before starting this medicine. Make sure to finish the full course of TB medicine.

Call your doctor or health care professional if you get a cold or other infection while receiving this medicine. Do not treat yourself. This medicine may decrease your body''s ability to fight infection.

Keep out of the reach of children.

Store unopened syringes or injectors in a refrigerator between 2 to 8 degrees C (36 to 46 degrees F). Keep in the original container until ready for use. Protect from light. Do not freeze. Do not shake. Prior to use, remove the syringe or injector from the refrigerator and use after 30 minutes at room temperature. Throw away any unused medicine after the expiration date on the label.