Tridesilon

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jul 31, 2023

Warnings

Tridesilon Risks, Warnings, and Complications

Using Tridesilon can cause serious adverse effects and complications in some people. Talk to your doctor about other treatment options for your skin condition if you are at a high risk of adverse events from this medication. Some of the risks of using Tridesilon include:

SKIN REACTIONS: Using large amounts of Tridesilon (desonide cream) or using it for longer than prescribed can cause skin irritation (rash, redness, burning, itching, dryness, inflammation), skin thinning, spider veins, stretch marks, and changes in skin color. Your doctor will prescribe the lowest dose of this medicine for the shortest period to treat your skin condition. Follow these instructions carefully and tell your doctor right away if you develop any new or worsening skin reactions.
SKIN INFECTIONS: Tridesilon (desonide) reduces the immune system’s ability to fight infections, including skin infections. The longer you use this medicine, the higher the risk of infections. Tell your doctor immediately if you notice any signs and symptoms of fungal or bacterial skin infections, such as redness, swelling, discomfort, or pus (oozing) in the area where you are using desonide.
HORMONAL CHANGES: Topical steroids such as Tridesilon can be absorbed through the skin and may have systemic effects on the body. For example, using too much topical steroid, using it for a long period of time, or applying it on large areas of the body can potentially lead to high blood sugar levels or easy bruising and bleeding. Using other similar drugs (topical steroids) at the same time can increase the risk. Covering the treated area with a bandage can also increase the absorption of the medicine into the body.
The risk of these side effects is rare with Tridesilon because it is a mild corticosteroid. However, do not use desonide for longer than prescribed (usually 2-4 weeks). Also, do not suddenly stop using the cream after using it for a long time, as this can cause steroid withdrawal symptoms such as itching, burning, and flaking of the skin

Precautions Before Starting Tridesilon

Tell your doctor if you have ever had an allergic reaction to Tridesilon (desonide), any of the active or inactive ingredients in Tridesilon cream, or any other medications. Your pharmacy can give you a list of ingredients.

Give your doctor and pharmacist a complete list of your medications, including prescription medications, over-the-counter medicines, vitamins, supplements, and herbal products. Make sure you mention other steroid medicines, including topical steroid creams, ointments, gels, foams, and lotions. This can help avoid possible interactions between your medications.

Give your doctor a complete medical history. Be sure to mention if you have diabetes, liver disease, or Cushing’s syndrome.

Tell your doctor if you are pregnant, could be pregnant, plan to get pregnant, or are nursing an infant with breast milk.

Precautions During Use of Tridesilon

Keep all your medical and lab appointments during Tridesilon treatment. Tell your doctor if you become pregnant while using this medicine. Tell all your doctors you are using desonide foam before any surgical procedures, including dental procedures.

Tridesilon Drug Interactions

Other drugs may affect how Tridesilon works. Possible interactions with other medicines can increase the risk of severe adverse effects.

Give your doctor or pharmacist a complete list of your medications, including prescription drugs, nonprescription drugs, dietary supplements, herbal remedies, and other topical medications (creams, ointments, foams, gels, and lotions). Also, tell your healthcare professional if you smoke, drink alcohol, or use recreational drugs because some of these substances can cause serious health complications when used with prescription and non-prescription medications.

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