Do not take this medicine with any of the following medications:

-azathioprine
-mercaptopurine

This medicine may also interact with the following medications:

-aminophylline
-certain medicines used to treat cancer
-pegloticase
-rasburicase
-theophylline

They need to know if you have any of these conditions:

-heart disease
-history of heart attack or stroke
-kidney disease
-liver disease
-taking azathioprine or mercaptopurine
-an unusual or allergic reaction to febuxostat, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast feeding

Visit your healthcare provider for regular checks on your progress. Tell your healthcare professional if your symptoms do not start to get better or if they get worse. You will need regular blood tests while you are taking this medicine.

Your gout may flare up when you are first taking this medicine. Do not stop taking this medicine, even if you have a flare. Your doctor or healthcare provider may give you another medicine to help treat the gout pain.

This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your healthcare provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips, or lymph nodes in your neck or under your arms.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.