What side effects may I notice from receiving Xeljanz XR?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-blood clot (chest pain; shortness of breath; pain, swelling, or warmth in the leg)
-dizziness
-infection (fever, chills, cough, sore throat, pain or trouble passing urine)
-liver injury (dark yellow or brown urine; general ill feeling or flu-like symptoms; loss of appetite, right upper belly pain; unusually weak or tired, yellowing of the eyes or skin)
-low red blood cell counts (trouble breathing; feeling faint; lightheaded, falls; unusually weak or tired)
-tears in the stomach or intestines (fever; stomach pain; sudden change in bowel habits)
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-diarrhea
-headache
-muscle pain
-runny nose
-sinus trouble

This list may not describe all possible side effects for Xeljanz XR. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.