Zanaflex

Medically Reviewed by Harshi Dhingra, M.D.

Last Reviewed: Jun 22, 2022

Pros & Cons


What are the pros and cons of Zanaflex (tizanidine)?

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  • Zanaflex starts working within 1-2 hours, and its effects last for 6-8 hours. This medicine can be taken as needed.
  • It is available in multiple strengths so that the dose can be customized. You can cut or crush the tablets. You can also sprinkle the contents of Zanaflex capsules on food. Talk to your doctor before you do this, however.
  • It is available as a low-cost generic. Zanaflex drug coupons from BuzzRx can help you save on the brand name medicine.

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  • You cannot take Zanaflex with fluvoxamine or ciprofloxacin.
  • Zanaflex may not be suitable for people over 65 or those with liver or kidney disease. 
  • This medicine can cause low blood pressure, dizziness, and falls.
  • Stopping Zanaflex suddenly can cause withdrawal symptoms such as muscle tightness, high blood pressure, and fast heart rate.